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A. CAPRANI**, B. MIRAMOR*, J. AVICENNE**, A. RICHERT**, E. RITA DE LIMA TEIXEIRA
* Caixa Postal 1394, Salvador Bahia (Brazil) CEP 40001 – 970,+ Policlinica Santa Paula, 2717 Av. Presidente Vargas – Ondina, Salvador Bahia (Brazil)
** Association « Positifs » BP 230 75865 Paris Cedex 18 (France)
OBJECTIVE
To test the efficiency of an herbal preparation of a mixture of 3 brazilian plants (CHAM3) on HIV+ patients.
METHOD
- Open trial (trial duration 9.23 months)
- 12 brazilian HIV patients (5 ARC and 7AIDS)
- 1992 – 1995
- posology: 100 ml 3 times a day of CHAM3 solution (about 1g/l of plant extract)
RESULTS
- Drastic improvement of clinical and biological parameters for all patients
- No opportunistic infection
- No side effects
|
| parameter |
before therapy (mean+/-SD) |
after therapy (mean+/-SD) |
significancy |
| p value Hb (g/l) |
12.38+/-2.13 |
12.58+/-2.05 |
0.97 |
| Leucocytes/mm3 |
5080+/-2061 |
4801+/-2270 |
0.75 |
| Lymphocytes/mm3 |
1585+/-852 |
1811+/-885 |
0.31 |
| Lymphocytes % |
3 2.35+/-13.9 |
39.33+/-12.8 |
0.071 |
| CD4 Lymphocytes/mm3 |
207+/-186 |
460+/-207 |
0.0025 |
| CD4 Lymphocytes % |
12,68 +/-7,65 |
22,47+/-6,74 |
0,01 |
| CD8 Lymphocytes/mm3 |
853+/-373 |
960+/-731 |
0.72 |
| CD8 Lymphocytes % |
54.1+/-8.2 4 |
65+/-11.8 |
0.07 |
| Monocytes/mm3 |
341+/-198 |
225+/-118 |
0.15 |
| |
| patients |
1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
9 |
10 |
11 |
12 |
| cd4/mm3 before |
19 |
45 |
49 |
68 |
93 |
108 |
144 |
274 |
288 |
385 |
396 |
620 |
| cd4/mm3 after. |
554 |
200 |
422 |
289 |
322 |
452 |
243 |
960 |
425 |
635 |
435 |
582 |
CONCLUSION
Cham3 appears to be an efficient agent in HIV infected brazilians patients, particularly in the more depressed ones. A similar investigation is in progress in Europe, in order to confirm or infirm these results. |
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